monolix Suite

2024R1
Lixoft develops modeling and simulation software for advanced model-based drug development. Its products offer powerful and easy solutions for population analysis in pre-clinical, clinical trials and in treatment individualization.
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2024R1
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Description

monolix Suite Overview

Lixoft develops modeling and simulation software for advanced model-based drug development. Its products offer powerful and easy solutions for population analysis in pre-clinical, clinical trials and in treatment individualization.

Lixoft’s technologies are the result of a ten years research program in statistics and modeling, led by Inria on non-linear mixed effect models for advanced population analysis, pharmacometrics, pre-clinical and clinical trial modeling & simulation.

Features of monolix Suite

  • Very intuitive interface
    PKanalix can be used via a graphical interface to easily define settings and rules, check the calculations and display the results. It can also be used via R for powerful scripting.
  • Straightforward NCA
    PKanalix calculates NCA parameters with industry-standard methods, and automatically generates a full set of plots to visualize the data, the distributions of calculated parameters and correlations with covariates.
  • Reliable and clear results
    All results are available as tables and summaries, and as interactive plots for a fast and intuitive interpretation. All settings are saved in the project for reproducible results, and the integrated validation suite ensures correct installation and calculation.
  • Compartmental analysis
    Calculation of the parameters in the Compartmental Analysis framework is also proposed with a large library of PK models. In addition, it includes a direct link toward population modeling using Monolix.
  • Monolix, the best tool for Model Based Drug Development
    Monolix is the most advanced and simple solution for non-linear mixed effects modeling (NLME) for pharmacometrics. It is based on the SAEM algorithm and provides robust, global convergence even for complex PK/PD models. Monolix is used for preclinical and clinical population PK/PD modeling and for Systems Pharmacology.
    Monolix enjoys a large user community. Monolix is widely used by academia, the pharmaceutical industry as well as the US regulatory agencies.
  • Advanced Statistical Methodologies
    Reliable convergence for all type of data is a centerpiece in population PKPD modeling, which is why Lixoft pioneered in collaboration with Inria the SAEM algorithm.
  • Automated generation of diagnostic tests
    Monolix automatically generates a full set of diagnostic plots even for complex PK/PD models. For example, you can instantaneously create the Visual Predictive Check, split by any patient subgroup you would want to investigate.
  • Increased productivity and quality
    Efficient C++ solver package, standardized model language with Mlxtran, PK/PD model library and integrated software all contribute to better productivity and quality.
  • Very easy to use with its GUI
    Our solutions are designed for ease of use. Monolix can be used via a graphical interface or command lines for powerful scripting. This means less programming for you and more focus on exploring models and pharmacology to deliver in time to your customers.

System Requirements for monolix Suite

RAM: 2 GB

Operating System: Windows 7, Windows 8, Windows 10, Windows 11, Windows server 2012, Windows server 2016, Windows server 2019, and Windows server 2022.

Space Required: 500 MB

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